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Adverse Effects with Nucleoside Analogs (Nukes)Nucleoside analogs emulate one of the four building blocks (nucleosides) of DNA, hence their name. Naturally such drugs interfere with DNA synthesis, causing problems with any organs or processes that rely on cell division, such as the replenishment of red and white blood cells. They also interfere with the energy regulating organelles known as mitochondria because they have their own DNA, without the protective mechanisms of the cell nucleus. It is most shocking that the most famous of these drugs, AZT, should be recommended for use by pregnant women. Also see information specifically related to AZT at http://aras.ab.ca/azt.html on this site.
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© Copyright February 15, 2016: Alberta Reappraising AIDS Society